Nephrotoxicity of urographic radiocontrast drugs
نویسندگان
چکیده
منابع مشابه
Molecular Mechanisms of Renal Cellular Nephrotoxicity due to Radiocontrast Media
Modern iodinated radiocontrast media are all based on the triiodinated benzene ring with various chemical modifications having been made over the last few decades in order to reduce their toxicity. However, CIN remains a problem especially in patients with pre-existing renal failure. In vitro studies have demonstrated that all RCM are cytotoxic. RCM administration in vivo may lead to a decrease...
متن کاملCharacterization of a novel model for investigation of radiocontrast nephrotoxicity.
OBJECTIVES Radiocontrast agents are one of the most common causes of acute renal failure in the world. These agents are required for both diagnostic and therapeutic modalities of medical intervention, including computed tomography (CT), angiography and cardiac catheterization. Publications over the past 40 years support three potential mechanisms of toxicity: oxidative stress, haemodynamics and...
متن کاملN-acetylcysteine for prevention of radiocontrast induced nephrotoxicity: the importance of dose and route of administration.
Dose and route of administration of N-acetylcysteine are key factors to consider when evaluating whether this agent is effective in preventing radiocontrast induced nephropathy.
متن کاملNephrotoxicity of low osmolar radiocontrast agents in patients with chronic renal failure.
Dr. P. Cacoub, Department of Nephrology, Hôpital Pitié-Salpêtrière, 47-83, boulevard de l’Hôpital, F-75651 Paris Cédex 13 (France) Dear Sir, Acute renal failure has long been recognized as a potential hazard of radiocontrast administration, especially in patients with preexisting renal failure [1]. Recently developed low osmolar agents have been considered less nephrotoxic, but some studies ind...
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BACKGROUND The United States is faced with an unprecedented epidemic of drug abuse. Every year thousands of Americans visit the emergency departments all over the country with illicit drug related complaints. These drugs have been known to be associated with a range of renal pathologies, from reversible acute kidney injuries to debilitating irreversible conditions like renal infarction. So far,...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1980
ISSN: 0085-2538
DOI: 10.1038/ki.1980.172